| Overview |
| bs-19654R-A350 |
| Phospho-OLIG2 (Ser10+Ser13+Ser14) Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated |
| WB, FCM |
| Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. |
| Human |
| Mouse, Rat, Cow, Chicken |
| Specifications |
| ALEXA FLUOR® 350 |
| Rabbit |
| KLH conjugated synthesized phosphopeptide derived from human OLIG2 around the phosphorylation site of Ser10+Ser13+Ser14: VS(pS)RP(pS)(pS)PE |
| Ser10+Ser13+Ser14 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 10215 |
| Q13516 |
| Cytoplasm, Nucleus |
| Olig2 (phospho S10 + S13 + S14); p-Olig2 (phospho S10 + S13 + S14); Basic domain helix loop helix protein class B 1; Basic helix loop helix protein class B 1; BHLHB; bHLHB1; bHLHe19; Class B basic helix loop helix protein 1; Class B basic helix-loop-helix protein 1; class E basic helix loop helix protein 19; Class E basic helix-loop-helix protein 19; Human protein kinase C binding protein RACK17; Olig2; OLIG2_HUMAN; Oligo2 ; Oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; Oligodendrocyte transcription factor 2; OTTHUMP00000067569; OTTHUMP00000067570; PRKCBP2; -binding protein RACK17; RACK17. |
| This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)( q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008] |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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