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beta-Synuclein Polyclonal Antibody, HRP Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Cow
  • Sheep
  • Rabbit
Overview
Catalog # bs-20682R-HRP
Product Name beta-Synuclein Polyclonal Antibody, HRP Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Mouse, Rat
Predicted Reactivity Human, Cow, Sheep, Rabbit
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human beta-Synuclein
Immunogen Range 51-100/140
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 6620
Swiss Prot Q16143
Subcellular location Cytoplasm, Nucleus
Synonyms 14 kDa brain-specific protein; Beta-synuclein; Phosphoneuroprotein 14; PNP14; Sncb; Synuclein beta; SYUB_HUMAN;
Background The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500