| Overview |
| bs-2792R-A555 |
| CRHR2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated |
| WB, IF(IHC-F), IF(ICC) |
| This antibody may cross react with CRHR1. |
| Human, Mouse |
| Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit |
| Specifications |
| ALEXA FLUOR® 555 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human CRHR2 |
| 51-150/411 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1395 |
| Q13324 |
| Cell membrane |
| CRF2; CRFR2; CRF-RB; HM-CRF; Corticotropin-releasing factor receptor 2; CRF-R-2; CRF-R2; CRFR-2; Corticotropin-releasing hormone receptor 2; CRH-R-2; CRH-R2; CRHR2; CRF2R; CRH2R |
| G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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