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Smoothened homolog Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
  • Cow
  • Pig
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-2801R-A680
Product Name Smoothened homolog Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated
Applications WB, IF(IHC-P)
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog, Cow, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation ALEXA FLUOR® 680
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Smoothened
Immunogen Range 551-650/787
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 6608
Swiss Prot Q99835
Subcellular location Cell membrane
Synonyms Gx; SMOH; FZD11; Smoothened homolog; SMO; Protein Gx
Background G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200