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JAM1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated

Applications

  • WB

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Dog
  • Cow
  • Pig
Overview
Catalog # bs-3651R-A647
Product Name JAM1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
Applications WB
Reactivity Rat
Predicted Reactivity Human, Mouse, Dog, Cow, Pig
Specifications
Conjugation ALEXA FLUOR® 647
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1
Immunogen Range 51-150/299
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 50848
Swiss Prot Q9Y624
Subcellular location Cell membrane
Synonyms JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; F11R; UNQ264/PRO301
Background Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Application Dilution
WB 1:300-5000