| Overview |
| bs-42069P-Biotin-100ug |
| Recombinant human GCH1 protein, C-His, Biotin Conjugated |
| Others |
| Others |
| Specifications |
| Biotin |
| Recombinant human GCH1 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 1-250/250 |
| Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Target |
| P30793 |
| GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions. |
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