New Small Molecule Antibody Collection Available - Click To View!

Recombinant human ACE2 protein, Biotin Conjugated

Applications

  • WB
  • ELISA

Reactivity

  • Human
Overview
Catalog # bs-43045P-Biotin
Product Name Recombinant human ACE2 protein, Biotin Conjugated
Applications WB, ELISA
Reactivity Human
Specifications
Conjugation Biotin
Source Recombinant human ACE2 is expressed from HEK293 cell with hFc Tag. It contains Gln18- Ser740.
Storage Buffer Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 59272
Swiss Prot Q9BYF1
Background

Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9], or the conversion of angiotensin II to angiotensin 1-7. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension. ACE2 receptors have been shown to be the entry point into human cells for some coronaviruses, including the SARS virus[10]. A number of studies have identified that the entry point is the same for SARS-CoV-2, the COVID-19 virus.