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Recombinant human ACE2 protein, C-hFc, PE-Cy5.5 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-43045p-pe-Cy5.5-1mg
Product Name Recombinant human ACE2 protein, C-hFc, PE-Cy5.5 Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation PE-Cy5.5
Source Recombinant human ACE2 protein, C-hFc protein is expressed in HEK293 with C-hFc. It contains the amino acid sequence of .
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 59272
Swiss Prot Q9BYF1
Background

Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9], or the conversion of angiotensin II to angiotensin 1-7. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension. ACE2 receptors have been shown to be the entry point into human cells for some coronaviruses, including the SARS virus[10]. A number of studies have identified that the entry point is the same for SARS-CoV-2, the COVID-19 virus.