| Overview |
| bs-43108P-APC-100ug |
| Recombinant human PTH1 Receptor protein, C-His (HEK293), APC Conjugated |
| Others |
| Others |
| Specifications |
| APC |
| Recombinant human PTH1 Receptor protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 27-188/593 |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Target |
| Q03431 |
| The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010] |