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Recombinant human PGC protein, C-His (HEK293), Biotin Conjugated

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-43143P-Biotin-100ug
Product Name Recombinant human PGC protein, C-His (HEK293), Biotin Conjugated
Applications Others
Reactivity Others
Specifications
Conjugation Biotin
Source Recombinant human PGC protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 17-388/388
Storage Buffer Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
Target
Swiss Prot P20142
Background This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq].