| Overview |
| bs-43161P-APC-100ug |
| Recombinant human HLA-E & Beta-2-MG Heterodimer protein, His&Avi (HEK293), APC Conjugated |
| Others |
| Others |
| Specifications |
| APC |
| Recombinant human HLA-E & Beta-2-MG Heterodimer protein is expressed in HEK293 cell with His&Avi . It contains the amino acid sequence of 22-305/358 |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Target |
| P13747 |
| HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. [provided by RefSeq, Jul 2008] |
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