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Recombinant mouse CD86 protein, C-His (HEK293), APC Conjugated

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-43590P-APC-100ug
Product Name Recombinant mouse CD86 protein, C-His (HEK293), APC Conjugated
Applications Others
Reactivity Others
Specifications
Conjugation APC
Source Recombinant mouse CD86 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 24-245/309
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Target
Swiss Prot P42082
Background This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].