| Overview |
| bs-43608P-Biotin-100ug |
| Recombinant human RANK protein, C-His (HEK293), Biotin Conjugated |
| Others |
| Others |
| Specifications |
| Biotin |
| Recombinant human RANK protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 30-212/616 |
| Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Target |
| Q9Y6Q6 |
| The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012] |
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