| Overview |
| bsm-61171r-bf647-100ul |
| PTPN6 Recombinant Antibody, AbBy Fluor-647 Conjugated |
| WB, IF |
| Human, Mouse |
| Rat |
| Specifications |
| AbBy Fluor-647 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human SHP1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5777 |
| P29350 |
| Nucleus |
| 70Z-SHP; EC 3.1.3.48; HCP; HCPH; PTN6; PTP-1C; PTP1C; PTPN6; SH-PTP1; SHP1. |
| Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis. |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
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