| Overview |
| bsm-62028R-APC |
| Niemann Pick C1 Like 1 Recombinant Antibody, APC Conjugated |
| WB |
| Human |
| Specifications |
| APC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human NPC1L1 |
| Recombinant |
| #REF! |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 29881 |
| Q9UHC9 |
| Cell membrane |
| NPC1 LIKE 1; NPC1L1. |
| Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia. |
| Application Dilution |
| WB |
1:300-5000 |
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