IDE Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
Overview | |
Catalog # | bs-0018R-A647 |
Product Name | IDE Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated |
Applications | IF(IHC-P) |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | ALEXA FLUOR® 647 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human IDE |
Immunogen Range | 514-564/1019 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage | Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months. |
Target | |
Gene ID | 3416 |
Swiss Prot | P14735 |
Subcellular location | Cytoplasm, Secreted, Cell membrane |
Synonyms | INSULYSIN; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; IDE |
Background | Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. |