IDE Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
| Overview | |
| Catalog # | bs-0018R-A647 |
| Product Name | IDE Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated |
| Applications | IF(IHC-P) |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | ALEXA FLUOR® 647 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IDE |
| Immunogen Range | 514-564/1019 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage | Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months. |
| Target | |
| Gene ID | 3416 |
| Swiss Prot | P14735 |
| Subcellular location | Cytoplasm, Secreted, Cell membrane |
| Synonyms | INSULYSIN; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; IDE |
| Background | Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. |