Caspase 9 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated

Applications

  • FCM
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
Overview
Catalog # bs-0049R-A647
Product Name Caspase 9 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
Applications FCM, IF(IHC-P)
Reactivity Human, Mouse, Rat, Dog
Specifications
Conjugation ALEXA FLUOR® 647
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Caspase 9 subunit p35
Immunogen Range 20-69/416
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target
Gene ID 842
Swiss Prot P55211
Subcellular location Cytoplasm
Synonyms MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Application Dilution
FCM 1:20-100
IF(IHC-P) 1:50-200