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Delta Opioid Receptor Polyclonal Antibody, PE-Cy7 Conjugated

Applications

  • WB

Reactivity

  • Human
  • Mouse

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Pig
  • Chicken
  • Rabbit
  • GuineaPig
Overview
Catalog # bs-10396R-PE-Cy7
Product Name Delta Opioid Receptor Polyclonal Antibody, PE-Cy7 Conjugated
Applications WB
Specificity This antibody may also have a weak secondary cross-reaction with Mu-type opioid receptor, which is primarily expressed in the adrenal gland and testis. This is predicted based upon a 79% non-contiguous sequence similarity.
Reactivity Human, Mouse
Predicted Reactivity Rat, Dog, Cow, Pig, Chicken, Rabbit, GuineaPig
Specifications
Conjugation PE-Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human OPRD1
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4985
Swiss Prot P41143
Subcellular location Cell membrane
Synonyms OPRD; Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1
Background G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Application Dilution
WB 1:300-5000