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HHV11 DNA polymerase catalytic subunit Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Virus
Overview
Catalog # bs-10489R-HRP
Product Name HHV11 DNA polymerase catalytic subunit Polyclonal Antibody, HRP Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Specificity This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit
Reactivity Virus
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Subcellular location Nucleus
Synonyms DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046.
Background Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500