| Overview |
| bs-11640R-A488 |
| Aph-1b Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated |
| WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Mouse |
| Human, Rat, Dog, Cow, Sheep, Pig |
| Specifications |
| ALEXA FLUOR® 488 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Aph-1b |
| 51-150/257 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 83464 |
| Q8WW43 |
| Cell membrane |
| PSFL; APH-1B; PRO1328; TAAV688; Gamma-secretase subunit APH-1B; Aph-1beta; Presenilin-stabilization factor-like; APH1B; UNQ688/PRO1328 |
| Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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