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    SCGN/Secretagogin Polyclonal Antibody, Biotin Conjugated

    Catalog # bs-11754R-Biotin
    Product Name SCGN/Secretagogin Polyclonal Antibody, Biotin Conjugated
    Applications WB, IHC-P
    Reactivity Human, Mouse, Rat
    Conjugation Biotin
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human Secretagogin
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
    Synonyms Calbindin like; CALBL; DJ501N12.8; Scgn; SECRET; Secretagogin; Secretagogin EF hand calcium binding protein; SEGN; SEGN_HUMAN; Setagin.
    Background SCGN is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.