0 Cart
Added to Cart
    You have items in your cart
    You have 1 item in your cart
    Check Out Continue Shopping

    MPPED2/Brain protein 239 Antibody, Cy5 Conjugated

    Catalog # bs-11888R-Cy5
    Product Name MPPED2/Brain protein 239 Antibody, Cy5 Conjugated
    Applications IF(IHC-P)
    Reactivity Human, Mouse, Rat
    Conjugation Cy5
    Host Rabbit
    Source KLH conjugated synthetic peptide derived from human MPPED2/Brain protein 239
    Clonality Polyclonal
    Isotype IgG
    Concentration 1ug/ul
    Purification Purified by Protein A.
    Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
    Synonyms 239FB; Brain protein 239; C11orf8; Chromosome 11 open reading frame 8; D11S302E; dJ1024C24.1; dJ873F21.1; FAM 1B; FAM1B; Fetal brain protein 239; Hs.46638; Metallophosphoesterase domain containing 2; Metallophosphoesterase domain containing protein 2; MPPED 2; MPPD2_HUMAN.
    Background MPPED2 (Metallophosphoesterase domain-containing protein 2), also known as C11orf8, FAM1B or 239FB, is a 294 amino acid protein. Expressed primarily in fetal brain tissue, MPPED2 is encoded by a gene that maps to chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double stranded DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.