ACBD3 Polyclonal Antibody, Biotin Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-11910R-Biotin-100uL |
| Product Name | ACBD3 Polyclonal Antibody, Biotin Conjugated |
| Applications |
ELISA
IHC-P
IHC-F
|
| Predicted Reactivity | Human, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ACBD3/GOCAP1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | ACBD 3; ACBD3; Acyl CoA binding domain containing protein 3; Acyl Coenzyme A binding domain containing 3; Acyl-CoA-binding domain-containing protein 3; GCP 60; GCP60; GCP60_HUMAN; GOCAP 1; GOCAP1; Golgi complex associated protein 1 60kDa; Golgi complex associated protein 1; Golgi complex-associated protein 1; Golgi phosphoprotein 1; Golgi resident protein GCP60; GOLPH 1; GOLPH1; PAP 7; PAP7; PBR and PKA associated protein 7; PBR associated protein; PBR- and PKA-associated protein 7; Peripheral benzodiazepine receptor associated protein PAP7; Peripheral benzodiazepine receptor-associated protein PAP7; Peripherial benzodiazepine receptor associated protein; PKA RIalpha associated protein. |
| Background | ACBD3 (acyl-CoA-binding domain-containing protein 3), also known as GCP60 (Golgi resident protein GCP60), GOCAP1, PAP7 or GOLPH1, is a Golgi apparatus membrane protein that contains one ACB (acyl-CoA-binding) domain and one GOLD (Golgi dynamics) domain which is essential for its interaction with other proteins. Expressed ubiquitously with highest expression in ovary and testis, ACBD3 is responsible for maintaining Golgi structure and, through binding to Giantin (golgin subfamily B member 1), functions to mediate protein transport between the Golgi and the endoplasmic reticulum (ER). Changes in the subcellular location of ACBD3 trigger signaling cascades within the Golgi that regulate cell fate and cell cycle progression. Additionally, ACBD3 is thought to act as a peripheral-type benzodiazepine receptor-associated protein, possibly playing a role in hormonal regulation and steroid formation. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
Frequently asked questions
Which applications is ACBD3 Polyclonal Antibody, Biotin Conjugated (bs-11910R-Biotin) validated for, and at what dilution?
bs-11910R-Biotin is validated for ELISA (1:500-1000); IHC-P (1:200-400); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should bs-11910R-Biotin be stored?
Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ACBD3 Polyclonal Antibody, Biotin Conjugated (bs-11910R-Biotin)?
KLH conjugated synthetic peptide derived from human ACBD3/GOCAP1