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ZFP36L1/ERF1 Polyclonal Antibody, Cy5 Conjugated


  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)


  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Dog
  • Cow
  • Pig
  • Horse
Catalog # bs-12254R-Cy5
Product Name ZFP36L1/ERF1 Polyclonal Antibody, Cy5 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Rat
Predicted Reactivity Human, Mouse, Dog, Cow, Pig, Horse
Conjugation Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ZFP36L1/ERF1
Immunogen Range 101-200/338
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID 677
Subcellular location Nucleus
Synonyms Berg36; BRF1; Butyrate response factor 1; C3H1 type-like 1; cMG1; Early response factor Berg36; EGF response factor 1; EGF-response factor 1; ERF 1; ERF-1; ERF1; Protein TIS11B; RNF162B; TIS11B; TISB_HUMAN; ZFP36L1; Zinc finger protein 36; Zinc finger protein 36 C3H type like 1; zinc finger protein C3H type 36 like 1.
Background TIS11B is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3?-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200