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RTF1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-12261R-A488
Product Name RTF1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Predicted Reactivity Human, Mouse, Rat, Dog, Cow, Horse, Chicken, Rabbit
Specifications
Conjugation ALEXA FLUOR® 488
Host Rabbit
Source KLH conjugated synthetic peptide derived from human RTF1
Immunogen Range 231-350/710
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 23168
Subcellular location Nucleus
Synonyms CDG1N; GTL 7; GTL7; KIAA0252; Ortholog of mouse gene trap locus 7; RNA polymerase associated protein RTF1 homolog; RNA polymerase-associated protein RTF1 homolog; RTF 1; RTF1; Rtf1 Paf1/RNA polymerase II complex component homolog; RTF1_HUMAN; rtf1L; YGL244W;
Background RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these also stain stromal cells in the thymus.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200