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APOL4/Apolipoprotein L4 Antibody, Cy3 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Predicted Reactivity

  • Human
Overview
Catalog # bs-12499R-Cy3
Product Name APOL4/Apolipoprotein L4 Antibody, Cy3 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Predicted Reactivity Human
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human APOL4/Apolipoprotein L4
Immunogen Range 1-100/351
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 80832
Subcellular location Secreted
Synonyms APOL IV; ApoL-IV; APOL4; APOL4_HUMAN; Apolipoprotein L IV; Apolipoprotein L-IV; Apolipoprotein L4; APOLIV; CTA 212A2.2; OTTHUMP00000028937.
Background The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-IV (apolipoprotein L-IV), also known as APOL4, is a 351 amino acid protein that exists as multiple alternatively spliced isoforms, one of which is secreted. Expressed in spleen, placenta, spinal cord, uterus, testis and trachea, apoL-IV is thought to play a role in lipid exchange and transport throughout the body and may be involved in reverse cholesterol transport, specifically from peripheral cells to the liver. Overexpression of apoL-IV is associated with schizophrenia, suggesting that apoL-IV may play a role in the pathogenesis of neural disorders.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200