| Overview |
| bs-1371R-PE |
| Snail1/2/3 Polyclonal Antibody, PE Conjugated |
| WB, FCM |
| Human, Rabbit |
| Mouse, Rat |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Snail |
| 188-264/264 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 6615;6591;333929 |
| Q02085;P97469;Q9QY31 |
| Cytoplasm, Nucleus |
| dJ710H13.1; Protein sna; Protein snail homolog; SLUGH2; SNA; Sna protein; SNAH; SNAI1; Snail homolog 1 Drosophila; Zinc finger protein SNAI1; SNAI1_HUMAN; Protein snail homolog 1; dJ710H13.1; SNAIL; SNAIL1; Protein sna; SLUG; WS2D; SLUGH; SLUGH1; SNAIL2; SMUC; SNAIL3; ZNF293; Zfp293 |
| The zinc finger transcription factor 'SNAIL' was first identified in Drosophila and, along with 'twist', a basic helix-loop-helix transcription factor, is indispensable for mesoderm formation. SNAIL is a repressor of mouse E-cadherin transcription, with expression of SNAIL inversely correlated with expression of E-cadherin. Abnormal expression of SNAIL could underlie the tumorigenic conversion of epithelia associated with loss of E-cadherin expression through screening mouse and human cell lines and by in situ hybridization of primary human tumors undergoing malignant progression. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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