| Overview |
| bs-16311R-A594 |
| GRF2 Polyclonal Antibody , ALEXA FLUOR® 594 Conjugated |
| WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Mouse |
| Human, Rat, Cow, Sheep |
| Specifications |
| ALEXA FLUOR® 594 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GRF2 |
| 20-120/1237 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5924 |
| O14827 |
| Cytoplasm |
| GRF2; RAS-GRF2; Ras-specific guanine nucleotide-releasing factor 2; Ras guanine nucleotide exchange factor 2; RASGRF2 |
| Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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