| Overview |
| bs-1720R-A647 |
| JUP/gamma Catenin Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated |
| WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| This antibody may have minor cross-reactivity with catenin beta-1 based upon 75% non-contiguous sequence similarity. |
| Human |
| Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
| Specifications |
| ALEXA FLUOR® 647 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Cateninma gamma |
| 601-700/745 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3728 |
| P14923 |
| Cytoplasm, Cell membrane |
| DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12; Junction plakoglobin; Catenin gamma; Desmoplakin III; Desmoplakin-3; JUP |
| Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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