SPDEF Polyclonal Antibody, APC-Cy7 Conjugated

Applications

FCM
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human
Mouse
Rat

Predicted Reactivity

Dog
Cow
Horse
Chicken
Rabbit

Overview
Catalog #	bs-1866R-APC-Cy7
Product Name	SPDEF Polyclonal Antibody, APC-Cy7 Conjugated
Applications	FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human, Mouse, Rat
Predicted Reactivity	Dog, Cow, Horse, Chicken, Rabbit
Specifications
Conjugation	APC-Cy7
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human PDEF
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	25803
Subcellular location	Nucleus
Synonyms	bA375E1.3; PDEF; Prostate derived Ets factor; PROSTATE EPITHELIUM SPECIC ETS TRANSCRIPTION FACTOR; Prostate epithelium-specic Ets transcription factor; Prostate specic Ets; Prostate-derived Ets factor; Prostate-specic Ets; PSE; RP11-375E1__A.3; SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR; SAM pointed domain-containing Ets transcription factor; Spdef; SPDEF_HUMAN.
Background	SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma.
Application Dilution
FCM	1:20-100
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200

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