| Overview |
| bs-20197R-A680 |
| OPRD1 (Ser363) Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated |
| WB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
| This phosphorylation site is homologous in the listed cross reactive species at the specified location. |
| Human, Mouse, Rat |
| Cow, Chicken, Rabbit |
| Specifications |
| ALEXA FLUOR® 680 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human OPRD1 around the phosphorylation site of TP(p-S)DG |
| Ser363 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4985 |
| P41143 |
| Cell membrane |
| OPRD; Delta-type opioid receptor; D-OR-1; DOR-1; OPRD1 |
| G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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