| Overview |
| bs-2736R-A680 |
| IRS-1(Ser307) Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated |
| FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
| This phosphorylation site is homologous to Ser302 in Mouse and Rat. |
| Human, Mouse, Rat, Goat |
| Dog, Cow, Pig, Horse, Rabbit |
| Specifications |
| ALEXA FLUOR® 680 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human IRS1 around the phosphorylation site of Ser307 [TE(p-S)IT] |
| Ser307 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3667 |
| P35568 |
| Cell membrane |
| HIRS-1; Insulin receptor substrate 1; IRS-1; IRS1 |
| May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). |
| Application Dilution |
| FCM |
1:20-100 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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