| Overview |
| bs-3288R-A647 |
| MYPT1 (Thr853) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated |
| IF(IHC-P), IF(IHC-F), IF(ICC) |
| This phosphorylation site is homologous to that of Thr852 in Mouse and Thr855 in Rat. |
| Mouse, Rat |
| Human, Dog, Cow, Horse, Chicken, Rabbit |
| Specifications |
| ALEXA FLUOR® 647 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human around the phosphorylation site of Thr853 |
| Thr853 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4659 |
| O14974 |
| Cytoplasm |
| MBS; M130; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit; PPP1R12A |
| Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity. |
| Application Dilution |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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