Jagged 2 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Cow
  • Pig
Overview
Catalog # bs-4244R-Biotin
Product Name Jagged 2 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P
Specificity There is a chance that this protein will cross-react with JAG1 based on 77% sequence similarity
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Cow, Pig
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Jagged 2
Immunogen Range 201-300/1238
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3714
Swiss Prot Q9Y219
Subcellular location Cell membrane
Synonyms D12Ggc2e; HJ 2; HJ2; JAG 2; JAG2; Jagged 2 precursor; Jagged2; Syndactylism.
Background Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
Application Dilution
WB 1:300-1000
ELISA 1:500-1000
IHC-P 1:200-400