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beta 2 Defensin Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Rat

Predicted Reactivity

  • Human
Overview
Catalog # bs-4307R-A750
Product Name beta 2 Defensin Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Rat
Predicted Reactivity Human
Specifications
Conjugation ALEXA FLUOR® 750
Host Rabbit
Source KLH conjugated synthetic peptide derived from human beta 2 Defensin
Immunogen Range 24-64/64
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 1673
Swiss Prot O15263
Subcellular location Secreted
Synonyms BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB12; Beta-defensin 4A; Beta-defensin 2; Defensin, beta 2; Skin-antimicrobial peptide 1; DEFB4A
Background Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200