| Overview |
| bs-5409R-HRP |
| LRP1(Ser4523) Polyclonal Antibody, HRP Conjugated |
| ELISA, IHC-P, IHC-F |
| This is the corresponding phosphorylation site in the following species: mouse ser(4524) rat ser(4524) |
| Human, Rat |
| Mouse |
| Specifications |
| HRP |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human LRP1 around the phosphorylation site of Ser4523 |
| Ser4523 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4035 |
| Q07954 |
| Cytoplasm, Nucleus, Cell membrane, Extracellular matrix |
| APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R; Prolow-density lipoprotein receptor-related protein 1; LRP-1; Alpha-2-macroglobulin receptor; Apolipoprotein E receptor; LRP1 |
| Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Functions as a receptor for Pseudomonas aeruginosa exotoxin A. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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