Ac-Trp-Leu-Ala-AMC
| Overview | |
| Catalog # | bs-75318c-1mg |
| Product Name | Ac-Trp-Leu-Ala-AMC |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 1 year after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 1104011-59-7 Molecular formula: C32H37N5O6 Molecular weight: 587.7 Purity: >98% (HPLC) Appearance: Lyophilized powder. Solubility: Soluble in DMSO. InChiKey: PIJMRHCPKXLMIS-DOYMOWJKSA-N SMILES: CC(C1=CC=C(C=C1O2)NC([C@H](C)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=CC2=O |
| Description | Fluorogenic peptide substrate for measuring chymotrypsin-like activity of the 20S proteasome. This substrate is hydrolyzed by the beta5-subunit of the 20S proteasome to generate detectable fluorescence. 20S Proteasome enzyme requires activation with 0.035% SDS in the assay buffer. Excitation: 345nm. Emission: 445nm. Specific substrate to the constitutive proteasome, not hydrolyzed efficiently by the immunoproteasome. This substrate is useful for inhibitor screening and kinetic analysis. |
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