UMPS Polyclonal Antibody, AbBy Fluor® 555 Conjugated

Applications

WB
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human
Rhesus Monkey
Cynomolgus Monkey

Predicted Reactivity

Mouse
Rat
Dog
Cow
Sheep
Horse
Rabbit

Overview
Catalog #	bs-8110R-BF555
Product Name	UMPS Polyclonal Antibody, AbBy Fluor® 555 Conjugated
Applications	WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human, Rhesus Monkey, Cynomolgus Monkey
Predicted Reactivity	Mouse, Rat, Dog, Cow, Sheep, Horse, Rabbit
Specifications
Conjugation	AbBy Fluor® 555
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human UMPS
Immunogen Range	351-450/480
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	7372
Swiss Prot	P11172
Subcellular location	Cytoplasm
Synonyms	Uridine 5'-monophosphate synthase; UMPS; UMP synthase; Orotate phosphoribosyltransferase; OPRT; OPRTase; ODC; OMPdecase; OK/SW-cl.21
Background	This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Application Dilution
WB	1:300-5000
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200

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