DEPTOR Polyclonal Antibody, Cy3 Conjugated

Applications

  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-8255R-Cy3
Product Name DEPTOR Polyclonal Antibody, Cy3 Conjugated
Applications IF(IHC-P)
Reactivity Human, Mouse
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DEPTOR/DEPDC6
Immunogen Range 62-107/409
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target
Gene ID 64798
Swiss Prot Q8TB45
Synonyms DEP.6; DEPDC6; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; DEPTOR
Background DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Application Dilution
IF(IHC-P) 1:50-200