| Overview |
| bs-9060R-Biotin |
| DVL2 (Thr224) Polyclonal Antibody, Biotin Conjugated |
| WB, IHC-P |
| This antibody will recognize DVL3 when phosphorylated at Thr205 |
| Human, Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224 |
| Thr224 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 1856 |
| O14641 |
| Cytoplasm |
| Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2; DVL2 |
| Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
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