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C1orf2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-9782R-A555
Product Name C1orf2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
Applications WB, IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation ALEXA FLUOR® 555
Host Rabbit
Source KLH conjugated synthetic peptide derived from human C1orf2
Immunogen Range 151-250/668
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 10712
Synonyms Chromosome 1 open reading frame 2; COTE1; F189B_HUMAN; FAM189B; Family with sequence similarity 189 member B; Hypothetical protein LOC10712; Protein COTE1; Protein FAM189B.
Background COTE1, also known as FAM189B (family with sequence similarity 189, member B), is a 668 amino acid multi-pass membrane protein that is widely expressed and belongs to the FAM189 family. Existing as two alternatively spliced isoforms, COTE1 is encoded by a gene that maps to human chromosome 1q22. As the largest human chromosome, chromosome 1 spans about 260 million base pairs and makes up approximately 8% of the human genome. Hutchinson-Gilford progeria, a rare aging disorder, is associated with the LMNA gene which is located on chromosome 1. Familial adenomatous polyposis, Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200