Overview |
bsm-33089M-APC-Cy7 |
IDE Monoclonal Antibody, APC-Cy7 Conjugated |
WB |
Human |
Specifications |
APC-Cy7 |
Mouse |
KLH conjugated synthetic peptide derived from human IDE |
Monoclonal |
5H4 |
IgG |
1ug/ul |
Purified by Protein G. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3416 |
P14735 |
Extracellular, Cytoplasm, Cytomembrane |
BC2; Insulin degrading enzyme; FLJ35968; insulin protease; insulinase; insulysin; Abeta-degrading protease; FLJ35968; Ide; IDE_HUMAN; Insulin-degrading enzyme; OTTHUMP00000020097. |
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. |
Application Dilution |
WB |
1:300-5000 |