beta 2 Microglobulin (4G1) Monoclonal Antibody

$Lane 1: Raji cell; Lane 2: U937 cell; Probed with beta 2 Microglobulin (4G1) Monoclonal Antibody (bsm-52425R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.$

Lane 1: Raji cell; Lane 2: U937 cell; Probed with beta 2 Microglobulin (4G1) Monoclonal Antibody (bsm-52425R) at 1:1000 overnight at 4\u00b0C followed by a conjugated secondary antibody for 60 minutes at 37\u00b0C.

$IF(ICC) staining with beta 2 Microglobulin (4G1) Monoclonal Antibody (bsm-52425R) at 1:100 in A431 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.$

IF(ICC) staining with beta 2 Microglobulin (4G1) Monoclonal Antibody (bsm-52425R) at 1:100 in A431 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100\/PBS.

Applications

WB
IHC-P
IF(ICC)

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bsm-52425R
Product Name	beta 2 Microglobulin (4G1) Monoclonal Antibody
Applications	WB, IHC-P, IF(ICC)
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Human beta 2 Microglobulin between 1-100 amino acids
Clonality	Monoclonal
Clone #	4G1
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	567
Swiss Prot	P61769
Synonyms	Beta-2-microglobulin, B2M; CDABP0092; HDCMA22P
Background	Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Application Dilution
WB	1:300-5000
IHC-P	1:200-400
IF(ICC)	1:50-200

Applications

Reactivity

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