| Overview |
| bsm-52561r-bf680-100ul |
| F11R/JAM-A/CD321 Recombinant Antibody, AbBy Fluor-680 Conjugated |
| WB |
| Human |
| Mouse, Rat |
| Specifications |
| AbBy Fluor-680 |
| Rabbit |
| Human Junctional Adhesion Molecule 1 between 28-241 amino acids |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 50848 |
| Q9Y624 |
| Cell membrane, Extracellular domain, Cell junction |
| Junctional adhesion molecule A; Junctional adhesion molecule 1; Platelet F11 receptor; Platelet adhesion molecule 1; CD321; JAM-A; JAMA; JAM-1; JAM1; PAM-1; F11R |
| Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
| Application Dilution |
| WB |
1:300-5000 |
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