| Overview |
| bsm-54116R |
| RRM2 (8H2) Monoclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| Recombinant protein within human RRM2 aa 1-200 |
| Monoclonal |
| 8H2 |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
| Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Target |
| 6241 |
| P31350 |
| Ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; RRM2; RR2; |
| Belongs to the ribonucleoside diphosphate reductase small chain family. Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.it have two regulatory sites: the specificity site, which controls substrate specificity, and the activity site which regulates overall catalytic activity. A substrate-binding catalytic site, located on M1, is formed only in the presence of the second subunit M2. |
| Application Dilution |
| WB |
1:300-5000 |
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