APLP2 Monoclonal Antibody

$Paraformaldehyde-fixed, paraffin embedded Rat testis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with APLP2 Monoclonal Antibody, Unconjugated (bsm-54736R) at 1:50 for 30 minutes at room temperature, DAB staining.$

Paraformaldehyde-fixed, paraffin embedded Rat testis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with APLP2 Monoclonal Antibody, Unconjugated (bsm-54736R) at 1:50 for 30 minutes at room temperature, DAB staining.

$Paraformaldehyde-fixed, paraffin embedded Human kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with APLP2 Monoclonal Antibody, Unconjugated (bsm-54736R) at 1:50 for 30 minutes at room temperature, DAB staining.$

Paraformaldehyde-fixed, paraffin embedded Human kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37\u00b0C for 30min; Antibody incubation with APLP2 Monoclonal Antibody, Unconjugated (bsm-54736R) at 1:50 for 30 minutes at room temperature, DAB staining.

Applications

WB
IHC-P

Reactivity

Human
Rat

Overview
Catalog #	bsm-54736R
Product Name	APLP2 Monoclonal Antibody
Applications	WB, IHC-P
Reactivity	Human, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Synthetic peptide within N-terminal Human APLP2.
Clonality	Monoclonal
Clone #	6H54
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	334
Swiss Prot	Q06481
Subcellular location	Nucleus, Cell membrane
Synonyms	amyloid beta (A4) precursor like protein 2 antibody, Amyloid like protein 2 antibody, Amyloid precursor protein homolog HSD 2 antibody, amyloid precursor protein homolog HSD2 antibody, Amyloid protein homolog antibody, Amyloid-like protein 2 antibody, APLP-2 antibody, Aplp2 antibody, APLP2_HUMAN antibody, APPH antibody, APPL2 antibody, CDEBP antibody, CDEI box binding protein antibody, CDEI box-binding protein antibody
Background	APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24. May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Application Dilution
WB	1:300-5000
IHC-P	1:200-400

Applications

Reactivity

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