Overview |
bsm-61303r-cy7 |
INPP4B Recombinant Antibody, Cy7 Conjugated |
WB, FCM |
Human, Mouse, Rat |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human INPP4B |
Monoclonal |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
8821 |
O15327 |
Cytoplasm |
4-bisphosphate 4-phosphatase; Inositol polyphosphate 4 phosphatase type II 105kDa; Inositol polyphosphate 4-phosphatase type II; Inpp4b; MGC132014; Type II inositol 3,4 bisphosphate 4 phosphatase; Type II inositol-3. |
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate. Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles.The lipid phosphatase activity is critical for tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |