| Overview |
| bs-20341R-Cy3 |
| Smad2 (Ser250) Polyclonal Antibody, Cy3 Conjugated |
| WB |
| Mouse, Rat |
| Human, Dog, Cow, Pig |
| Specifications |
| Cy3 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Anti-phospho-Smad2 (Ser250) |
| Ser250 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4087 |
| Q15796 |
| Cytoplasm, Nucleus |
| Mothers against decapentaplegic homolog 2; SMAD2; MAD homolog 2; Mothers against DPP homolog 2; JV18-1; Mad-related protein 2; hMAD-2; SMAD family member 2; MADH2; MADR2 |
| Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. |
| Application Dilution |
| WB |
1:300-5000 |
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