Overview |
bs-6773R |
A1CF Polyclonal Antibody |
ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC) |
Mouse, Rat |
Human, Cow, Sheep, Pig |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human A1CF |
101-200/594 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
29974 |
Cytoplasm, Nucleus |
A1CF; A1CF_HUMAN; ACF; ACF64; ACF65; Apo B RNA editing protein; Apobec 1 complementation factor; Apobec 1 complementation factor ACF ASP; APOBEC 1 stimulating protein; APOBEC1 complementation factor; APOBEC1 stimulating protein; APOBEC1-stimulating protein; APOBEC1CF; ASP; MGC163391; RP11-564C4.2. |
Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay. |
Application Dilution |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |