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Adenylate Cyclase III Antibody

Applications

  • WB
  • IHC
  • ICC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-70003R
Product Name Adenylate Cyclase III Antibody
Applications WB, IHC, ICC
Specificity Specific for endogenous levels of the ~160 kDa adenylate cyclase III protein.
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat adenylate cyclase III, conjugated to keyhole limpet hemocyanin (KLH).
Clonality Polyclonal
Isotype IgG
Concentration Lot Dependent
Purification Antigen Affinity purification
Storage Buffer PBS + 50% glycerol and 5 mm NaN3
Storage Condition Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Target
Gene ID 64508
Swiss Prot P21932
Synonyms AC-III antibody, AC3 antibody, ADCY3 antibody, ADCY3_HUMAN antibody, adenylate cyclase 3 antibody, Adenylate cyclase antibody, Adenylate cyclase type 3 antibody, Adenylate cyclase type III antibody, Adenylyl cyclase 3 antibody, ATP pyrophosphate lyase antibody, ATP pyrophosphate-lyase 3 antibody, olfactive type antibody
Background Adenylate cyclase is the enzyme which produces the "second messenger" signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011).
Application Dilution
WB 1:300-5000
IHC
ICC 1:100-500